Hello! I'm Aisiri H U V
MS Biotechnology candidate at Johns Hopkins University with hands-on research experience across trans-
lational oncology, immunotherapy, and computational biology. Skilled in both wet and dry lab workflows
with a long-term vision to develop accessible, real-world treatments.
AISIRI H U V
Biotechnology graduate
Email:
Address:
AGB layout, Mahalakshmipuram, Bangalore
EDUCATION
2027
Johns Hopkins University
MS in Biotechnology
2025
Biotechnology B.E
RV College of Engineering
2020
Pre University
BASE PU College
2018
High School
VVS Sardar Patel High School
EXPERIENCE
Oct 2024 - Jan 2025
Aurigene Oncology Limited
Research and Development Intern
Gained hands-on experience in cell and gene therapy department focusing on Rapid CAR T technology. Working under the guidance of renowned expert Dr. Kiran Kundu.
June 2024 - December 2024
Research Intern at Medical Oncology
Sammprada Hospital
Contributed to a retrospective study investigating the prognostic impact of inflammatory markers, clinical parameters, and treatment regimens on patient outcomes in oncology through data analysis and manuscript preparation.
Nov 2023
BRAINS Super Speciality Hospital
Research Intern
Analyzed diabetic neuropathy risk factors and cerebrospinal fluid biomarkers under Dr. N.K. Venkataramana for early intervention strategies.
Dec 2022 - May 2023
Research Intern
Centre of Excellence Computational Genomics
Conducted NGS analysis of colorectal cancer exome datasets and developed a cancer diagnosis pipeline using ML algorithms.
Nov 2022 - Dec 2022
Industry Intern
Anthem Biosciences Pvt Ltd
Gained comprehensive training in biopharmaceutical upstream and downstream processes of Serratiopeptidase and MK7.
SKILLS
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Docking
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Exploratory data analysis
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NGS analysis,
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Python
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C
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SPSS
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Basics of machine learning.
PROJECTS
In Silico Design of Neoantigen mRNA Vaccines Delivered via Lipid Nanoparticles for Glioblastoma (Ongoing)
mRNA vaccines targeting tumor-specific neoantigens, leveraging lipid nanoparticles for efficient delivery and enhanced immune response in cancer therapy.
Optimizing CAR T Cell Therapy for Glioblastoma
Explored strategies to overcome antigen heterogeneity and tumor microenvironment challenges, focusing on improving target selection and advancing personalized immunotherapy.
In Silico Computational Analysis of Colorectal Cancer Exome Datasets
Analyzed 20 cancer exome datasets to identify molecular markers for early detection, leading to the discovery of CD82 and ANO1 as promising candidates.
Predicting Parkinson’s Disease Progression Using Machine Learning and CSF Biomarkers (Ongoing)
Employed machine learning to analyze CSF biomarkers and disease severity, identifying potential markers to support personalized treatment plans for Parkinson’s disease.
Report
Predicting Diabetic Neuropathy In High Risk Populations
Conducting a prospective study on diabetic neuropathy to analyze key risk factors, enabling early intervention and improved patient outcomes
Study Proposal
Preclinical Assessment of a Combination Drug for Parkinson’s Disease
Investigated the efficacy of an L-DOPA and Ceftriaxone combination in mouse models, optimizing interactions to enhance anti-aggregation activity for Parkinson’s treatment.
Report
PUBLICATIONS
“In Silico Target Tracking: Molecular docking and pharmacokinetic studies of naturally occurring flavonoid glycosides and their activity against COVID-19 viral proteins” (Jan. 2025). In: IEEE Xplore 9.8, pp. 1– 6 https://doi.org/10.1109/CSITSS64042.2024.10816936.
“Flavonoids As Potential Antibacterial Agents: Targeting DNA Gyrase With Insights On Mechanistics” (2024). In: Journal Of Novel Research And Innovative Development 2.6, pp. 2200–2300. url: https: //www.tijer.org/jnrid/viewpaperforall.php?paper=JNRID2406027.
“A Critical Review of Phaseolamin’s Potential for Weight Loss in the Fight Against Obesity” (Aug. 2024).
In: Metszet Scientific Journal 9.8, pp. 409–415. url: https://metszetjournal.com/volume-9-issue-8/
Bridging the Gap: Towards Effective CAR T-Cell Therapy for Glioblastoma” (Jan. 2025). In: Gradiva
Review Journal 11.1, pp. 503–511. url: https://gradivareview.com/volume-11-issue-1-2025/.
"Machine Learning-Based Prediction of Parkinson’s Disease Progression Using CSF Biomarkers” (2025).
In: Submitted to Journal of Integrative Neuroscience, Under Review.
“Neoantigen mRNA Vaccines via Lipid Nanoparticles: A Review on Advancing Personalized Cancer Immunotherapy”
(Oct. 2024). In: Submitted to Frontiers in Immunology, Under Review.
RESEARCH ENGAGEMENTS AND CONFERENCE PRESENTATIONS
Presented a paper on ”In Silico Target Tracking: Molecular docking and pharmacokinetic studies of naturally occurring flavonoid glycosides and their activity against COVID-19 viral proteins.” at the 8th International Conference on Computational Systems and Information Technology for Sustainable Solutions 2024 organised by IEEE. Certificate
Poster Presentation of a paper titled ”Targeting the Unreachable: Revolutionizing CAR T Cell Therapy for Glioblastoma by Conquering Tumor Heterogeneity, Target Selection and Defying the Tumor Microenvironment” at Bengaluru Tech Summit (2023) Issued by Government Of Karnataka. Certificate
Presented a paper on ”Machine Learning-Powered Prediction of Parkinson’s Disease Trajectory” at the 6th Annual Convention of International Society Of Gene and Cell Therapy (2024).
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Presented a paper on ”Preclinical Assessment of a combination drug consisting of L-Dopa and Ceftriaxone in Mouse Models Simulating Parkinson’s Disease” at Shristi State Level Engineering Students Project Exhibition Competition (2022).
Best Paper Presentation Award for ”Protocol for Developing a Decision Support System(DSS) using Mutation patterns in individual cancers with application of AI and ML Technologies” at the International Conference on AIML-BIO organized by the Bangalore Bioinnovation Centre (2022).
COURSES AND CERTIFICATIONS
CO CURRICULAR ACTIVITIES
Organized two-week drama workshops for underprivileged school children to foster creativity and confidence.
As a part of of Genesis, RVCE’s Biotechnology Club, led events like ISGCT-AIMILBIO’24, Science and Power ’23, and organized the department fest Helix.
Volunteered with Youth for Seva at government schools in conducting menstrual health awareness sessions for adolescent girls.
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Taught government high school students to build a dummy simulation of dialysis through the Agastya Foundation, inspiring hands-on learning in biomedical concepts.
